Failure of Methyl Palmitate Induced Reticuloendothelial Blockade to Affect Plasma Levels of Factor VIII
نویسندگان
چکیده
منابع مشابه
Failure of methyl palmitate induced reticuloendothelial blockade to affect plasma levels of factor 8.
By EVELYN GAYNOR AND THEODORE H. SPAET T HE SITE OF antihemophihic globulin ( Factor VIII ) synthesis is unknown. Since implication of the reticuloendothelial system ( RES ) has been suggested by several investigators,1’4 and others5’#{176} have suspected a splenic role, the effects of RES blockade on plasma levels of Factor VIII have been studied. Methyl palmitate induces selective depression ...
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Protein specific aptamers are highly applicable affinity ligands in different fields of research and clinical applications. They have been developed against various targets, in particular, bio-macromolecules such as proteins. Among human proteins, the coagulation factors are the most attractive targets for aptamer selection and their specific aptamers had valuable characteristics in therapeutic...
متن کاملDevelopment of aptameric affinity ligands specific to human plasma coagulation factor VIII using SEC-SELEX
Protein specific aptamers are highly applicable affinity ligands in different fields of research and clinical applications. They have been developed against various targets, in particular, bio-macromolecules such as proteins. Among human proteins, the coagulation factors are the most attractive targets for aptamer selection and their specific aptamers had valuable characteristics in therapeutic...
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The dynamics of "reticuloendothelial blockade" were studied in living rabbits and isolated, perfused rabbit livers utilizing gelatin as a blockading agent and Au(198) stabilized in gelatin as a tracer. Employing the above experimental model, the following observations were made. (a) RES blockade was specific and dependent on the surface properties of the particle under study. (b) RES blockade w...
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Two patients with hemophilia A and antiquential antibody titers demonstrated no factor VIII antibodies were treated with change in antibody response in either infusions of factor VIII concentrates and patient when compared to previous studintravenous cyclophosphamide in an aties following factor VIII infusion alone. tempt to suppress the antibody response. These results are in contrast to the p...
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ژورنال
عنوان ژورنال: Blood
سال: 1966
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v28.4.595.595